Letter to the Editor: Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels: are dromedary camels a reservoir for MERS-CoV?

نویسندگان

  • E Karagoz
  • M Hatipoğlu
  • V Turhan
چکیده

To the Editor: In a recent issue of Eurosurveillance, we read the article by Nowotny et al. [1]. In this article, the authors concluded, based on phylogenetic analysis and a high Middle East respiratory coronavirus (MERS-CoV) load in nasal swabs of dromedary camels, that local zoonotic transmission of MERS-CoV from camels may be possible through the respiratory route. We would like to thank the authors for their contribution to the knowledge of MERS-CoV. However, we would like to report a few concerns regarding this study from a methodological point of view [1].

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منابع مشابه

Replication and Shedding of MERS-CoV in Upper Respiratory Tract of Inoculated Dromedary Camels

In 2012, a novel coronavirus associated with severe respiratory disease in humans emerged in the Middle East. Epidemiologic investigations identified dromedary camels as the likely source of zoonotic transmission of Middle East respiratory syndrome coronavirus (MERS-CoV). Here we provide experimental support for camels as a reservoir for MERS-CoV. We inoculated 3 adult camels with a human isola...

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Dromedary camels in northern Mali have high seropositivity to MERS-CoV

A high percentage (up to 90%) of dromedary camels in the Middle East as well as eastern and central Africa have antibodies to Middle East respiratory syndrome coronavirus (MERS-CoV). Here we report comparably high positivity of MERS-CoV antibodies in dromedary camels from northern Mali. This extends the range of MERS-CoV further west in Africa than reported to date and cautions that MERS-CoV sh...

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An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels.

Middle East respiratory syndrome coronavirus (MERS-CoV) infections have led to an ongoing outbreak in humans, which was fueled by multiple zoonotic MERS-CoV introductions from dromedary camels. In addition to the implementation of hygiene measures to limit further camel-to-human and human-to-human transmissions, vaccine-mediated reduction of MERS-CoV spread from the animal reservoir may be envi...

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Antibodies against MERS Coronavirus in Dromedary Camels, United Arab Emirates, 2003 and 2013

Middle East respiratory syndrome coronavirus (MERS-CoV) has caused an ongoing outbreak of severe acute respiratory tract infection in humans in the Arabian Peninsula since 2012. Dromedary camels have been implicated as possible viral reservoirs. We used serologic assays to analyze 651 dromedary camel serum samples from the United Arab Emirates; 151 of 651 samples were obtained in 2003, well bef...

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Authors reply: Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels: are dromedary camels a reservoir for MERS-CoV?

In fact, we mentioned in our paper [2] in detail that the cycle threshold (Ct) values in nasal and conjunctival swabs of the five MERS-CoV reverse transcriptionquantitative polymerase chain reaction (RT-qPCR) positive Omani camels ranged from as low as 15.74 to 36.29, indicating a high viral load in the former. Our results were confirmed in a recent report by Raj et al. [3], who demonstrated an...

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عنوان ژورنال:
  • Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

دوره 19 20  شماره 

صفحات  -

تاریخ انتشار 2014